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Overactivation of Hedgehog Signaling Alters Development of the Ovarian Vasculature in Mice

The hedgehog (HH) signaling pathway is critical for ovarian function in Drosophila, but its role in the mammalian ovary has not been defined. Previously, expression of a dominant active allele of the HH signal transducer protein smoothened (SMO) in Amhr2(cre/+)SmoM2 mice caused anovulation in associ...

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Autores principales: Ren, Yi, Cowan, Robert G., Migone, Fernando F., Quirk, Susan M.
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for the Study of Reproduction, Inc. 2012
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3386146/
https://ncbi.nlm.nih.gov/pubmed/22402963
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1095/biolreprod.112.099176
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