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Frequency and Geographic Distribution of gyrA and gyrB Mutations Associated with Fluoroquinolone Resistance in Clinical Mycobacterium Tuberculosis Isolates: A Systematic Review

BACKGROUND: The detection of mutations in the gyrA and gyrB genes in the Mycobacterium tuberculosis genome that have been demonstrated to confer phenotypic resistance to fluoroquinolones is the most promising technology for rapid diagnosis of fluoroquinolone resistance. METHODS: In order to characte...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Avalos, Elisea, Catanzaro, Donald, Catanzaro, Antonino, Ganiats, Theodore, Brodine, Stephanie, Alcaraz, John, Rodwell, Timothy
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376704/
https://ncbi.nlm.nih.gov/pubmed/25816236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120470
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