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Frequency and Geographic Distribution of gyrA and gyrB Mutations Associated with Fluoroquinolone Resistance in Clinical Mycobacterium Tuberculosis Isolates: A Systematic Review

BACKGROUND: The detection of mutations in the gyrA and gyrB genes in the Mycobacterium tuberculosis genome that have been demonstrated to confer phenotypic resistance to fluoroquinolones is the most promising technology for rapid diagnosis of fluoroquinolone resistance. METHODS: In order to characte...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Avalos, Elisea, Catanzaro, Donald, Catanzaro, Antonino, Ganiats, Theodore, Brodine, Stephanie, Alcaraz, John, Rodwell, Timothy
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376704/
https://ncbi.nlm.nih.gov/pubmed/25816236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0120470
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