A long noncoding RNA induced by TLRs mediates both activation and repression of immune response genes

An inducible program of inflammatory gene expression is central to anti-microbial defenses. Signal-dependent activation of transcription factors, transcriptional co-regulators and chromatin modifying factors collaborate to control this response. Here we identify a long noncoding RNA that acts as a k...

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Pubblicato in:Science
Autori principali: Carpenter, Susan, Atianand, Maninjay, Aiello, Daniel, Ricci, Emiliano, Gandhi, Pallavi, Hall, Lisa L., Byron, Meg, Monks, Brian, Henry-Bezy, Meabh, O’Neill, Luke A.J, Lawrence, Jeanne B., Moore, Melissa J., Caffrey, Daniel R., Fitzgerald, Katherine A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2013
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376668/
https://ncbi.nlm.nih.gov/pubmed/23907535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1240925
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