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A Natural Antisense Transcript, AS-IL1α, controls inducible transcription of the pro-inflammatory cytokine IL-1α

Natural antisense transcripts (NATs) are a class of long noncoding RNAs (lncRNAs) that are complementary to other protein-coding genes. Although thousands of NATs are encoded by mammalian genomes, their functions in innate immunity are unknown. Here, we identify and characterize a novel NAT, AS-IL1α...

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Vydáno v:J Immunol
Hlavní autoři: Chan, Jennie, Atianand, Maninjay, Jiang, Zhaozhao, Carpenter, Susan, Aiello, Daniel, Elling, Roland, Fitzgerald, Katherine A., Caffrey, Daniel R.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4530055/
https://ncbi.nlm.nih.gov/pubmed/26179904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1500264
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