A long noncoding RNA lincRNA-EPS acts as a transcriptional brake to restrain inflammation

Long intergenic noncoding RNAs (lincRNA) are important regulators of gene expression. Although lincRNAs are expressed in immune cells, their functions in immunity are largely unexplored. Here we identify an immunoregulatory lincRNA, lincRNA-EPS, that is precisely regulated in macrophages to control...

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Detalhes bibliográficos
Publicado no:Cell
Main Authors: Atianand, Maninjay K., Hu, Wenqian, Satpathy, Ansuman T., Shen, Ying, Ricci, Emiliano P., Alvarez-Dominguez, Juan R., Bhatta, Ankit, Schattgen, Stefan A., McGowan, Jason D., Blin, Juliana, Braun, Joerg E., Gandhi, Pallavi, Moore, Melissa J., Chang, Howard Y., Lodish, Harvey F., Caffrey, Daniel R., Fitzgerald, Katherine A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5289747/
https://ncbi.nlm.nih.gov/pubmed/27315481
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2016.05.075
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