LincRNA-p21 suppresses target mRNA translation

Mammalian long intergenic noncoding (linc)RNAs are best known for modulating transcription. Here we report a post-transcriptional function for lincRNA-p21 as a modulator of translation. Association of the RNA-binding protein HuR with lincRNA-p21 favored the recruitment of let-7/Ago2 to lincRNA-p21,...

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Bibliographic Details
Main Authors:	Yoon, Je-Hyun, Abdelmohsen, Kotb, Srikantan, Subramanya, Yang, Xiaoling, Martindale, Jennifer L., De, Supriyo, Huarte, Maite, Zhan, Ming, Becker, Kevin G., Gorospe, Myriam
Format:	Artigo
Language:	Inglês
Published:	2012
Subjects:	Article
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC3509343/ https://ncbi.nlm.nih.gov/pubmed/22841487 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2012.06.027
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LincRNA-p21 suppresses target mRNA translation

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