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The Nuclear Receptor FXR Uncouples the Actions of miR-33 from SREBP-2
OBJECTIVE: To determined whether activation of FXR alters cellular and plasma cholesterol homeostasis as a result of regulation of Srebp-2 and miR-33. APPROACH AND RESULTS: ChIP-seq data identified an FXR-response element within intron 10 of the Srebp-2 gene. Consistent with this observation, treatm...
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| Publicado no: | Arterioscler Thromb Vasc Biol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4376635/ https://ncbi.nlm.nih.gov/pubmed/25593129 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.114.304179 |
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