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MicroRNA-144 Regulates Hepatic ABCA1 and Plasma HDL Following Activation of the Nuclear Receptor FXR

RATIONALE: The bile acid receptor Farnesoid-X-Receptor (FXR) regulates many aspects of lipid metabolism by various complex and not fully understood molecular mechanisms. We set out to investigate the molecular mechanisms for FXR-dependent regulation of lipid and lipoprotein metabolism. OBJECTIVE: To...

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Detalhes bibliográficos
Main Authors: de Aguiar Vallim, Thomas Q., Tarling, Elizabeth J., Kim, Tammy, Civelek, Mete, Baldán, Ángel, Esau, Christine, Edwards, Peter A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3995747/
https://ncbi.nlm.nih.gov/pubmed/23519696
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.112.300648
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