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Nuclear Receptors and microRNA-144 Coordinately Regulate Cholesterol Efflux

The ATP-binding cassette transporter A1 (ABCA1) is a key mediator of cellular cholesterol efflux and HDL maturation. ABCA1 mRNA has an unusually long 3’ untranslated region, which makes it highly susceptible to microRNA (miRNA) targeting and repression. As such, multiple miRNAs have been reported to...

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Detalhes bibliográficos
Main Authors: Vickers, Kasey C., Rader, Daniel J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4043301/
https://ncbi.nlm.nih.gov/pubmed/23743223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.113.301422
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