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Nuclear Receptors and microRNA-144 Coordinately Regulate Cholesterol Efflux

The ATP-binding cassette transporter A1 (ABCA1) is a key mediator of cellular cholesterol efflux and HDL maturation. ABCA1 mRNA has an unusually long 3’ untranslated region, which makes it highly susceptible to microRNA (miRNA) targeting and repression. As such, multiple miRNAs have been reported to...

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Hlavní autoři: Vickers, Kasey C., Rader, Daniel J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2013
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4043301/
https://ncbi.nlm.nih.gov/pubmed/23743223
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/CIRCRESAHA.113.301422
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