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miR-33 links SREBP-2 induction to repression of sterol transporters

The sterol regulatory element binding protein 2 (SREBP-2) and the liver X receptor (LXR) control antagonistic transcriptional programs that stimulate cellular cholesterol uptake and synthesis, and cholesterol efflux, respectively. The clinical importance of SREBP-2 is revealed in patients with hyper...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Marquart, Tyler J., Allen, Ryan M., Ory, Daniel S., Baldán, Ángel
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: National Academy of Sciences 2010
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2901433/
https://ncbi.nlm.nih.gov/pubmed/20566875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1005191107
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