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miR-33 links SREBP-2 induction to repression of sterol transporters
The sterol regulatory element binding protein 2 (SREBP-2) and the liver X receptor (LXR) control antagonistic transcriptional programs that stimulate cellular cholesterol uptake and synthesis, and cholesterol efflux, respectively. The clinical importance of SREBP-2 is revealed in patients with hyper...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2901433/ https://ncbi.nlm.nih.gov/pubmed/20566875 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1005191107 |
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