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Anti-miR-33 Therapy Does Not Alter the Progression of Atherosclerosis in Low-Density Lipoprotein Receptor Deficient Mice

OBJECTIVE: To determine the efficacy of long-term anti-miR-33 therapy on the progression of atherosclerosis in high fat, high cholesterol-fed Ldlr(−/−) mice. METHODS AND RESULTS: Ldlr(−/−) mice received saline, or control or anti-miR-33 oligonucleotides once a week for 14 weeks. The treatment was ef...

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Detalhes bibliográficos
Main Authors: Marquart, Tyler J., Wu, Judy, Lusis, Aldons J., Baldán, Ángel
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587119/
https://ncbi.nlm.nih.gov/pubmed/23288159
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.112.300639
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