Lipidomic Analysis Links Mycobactin Synthase K to Iron Uptake and Virulence in M. tuberculosis

The prolonged survival of Mycobacterium tuberculosis (M. tb) in the host fundamentally depends on scavenging essential nutrients from host sources. M. tb scavenges non-heme iron using mycobactin and carboxymycobactin siderophores, synthesized by mycobactin synthases (Mbt). Although a general mechani...

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Dades bibliogràfiques
Publicat a:PLoS Pathog
Autors principals: Madigan, Cressida A., Martinot, Amanda Jezek, Wei, Jun-Rong, Madduri, Ashoka, Cheng, Tan-Yun, Young, David C., Layre, Emilie, Murry, Jeffrey P., Rubin, Eric J., Moody, D. Branch
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376628/
https://ncbi.nlm.nih.gov/pubmed/25815898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004792
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