Lipidomic Analysis Links Mycobactin Synthase K to Iron Uptake and Virulence in M. tuberculosis

The prolonged survival of Mycobacterium tuberculosis (M. tb) in the host fundamentally depends on scavenging essential nutrients from host sources. M. tb scavenges non-heme iron using mycobactin and carboxymycobactin siderophores, synthesized by mycobactin synthases (Mbt). Although a general mechani...

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Vydáno v:PLoS Pathog
Hlavní autoři: Madigan, Cressida A., Martinot, Amanda Jezek, Wei, Jun-Rong, Madduri, Ashoka, Cheng, Tan-Yun, Young, David C., Layre, Emilie, Murry, Jeffrey P., Rubin, Eric J., Moody, D. Branch
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
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Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376628/
https://ncbi.nlm.nih.gov/pubmed/25815898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004792
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