Lipidomic Analysis Links Mycobactin Synthase K to Iron Uptake and Virulence in M. tuberculosis

The prolonged survival of Mycobacterium tuberculosis (M. tb) in the host fundamentally depends on scavenging essential nutrients from host sources. M. tb scavenges non-heme iron using mycobactin and carboxymycobactin siderophores, synthesized by mycobactin synthases (Mbt). Although a general mechani...

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Detalhes bibliográficos
Publicado no:PLoS Pathog
Main Authors: Madigan, Cressida A., Martinot, Amanda Jezek, Wei, Jun-Rong, Madduri, Ashoka, Cheng, Tan-Yun, Young, David C., Layre, Emilie, Murry, Jeffrey P., Rubin, Eric J., Moody, D. Branch
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376628/
https://ncbi.nlm.nih.gov/pubmed/25815898
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004792
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