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Lipidomic analysis links mycobactin synthase K to iron uptake and virulence in M. tuberculosis.
The prolonged survival of Mycobacterium tuberculosis (M. tb) in the host fundamentally depends on scavenging essential nutrients from host sources. M. tb scavenges non-heme iron using mycobactin and carboxymycobactin siderophores, synthesized by mycobactin synthases (Mbt). Although a general mechani...
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Main Authors: | , , , , , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Public Library of Science (PLoS)
2015-03-01
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Colecção: | PLoS Pathogens |
Acesso em linha: | http://europepmc.org/articles/PMC4376628?pdf=render |
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