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Rigosertib induces cell death of a myelodysplastic syndrome-derived cell line by DNA damage-induced G2/M arrest
A multi-kinase inhibitor, rigosertib (ON 01910.Na) has recently been highlighted as a novel type of anti-cancer agent for the treatment of the myelodysplastic syndromes (MDS), but its action mechanisms remain to be clarified. We investigated the in vitro effects of rigosertib on an MDS-derived cell...
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Publicat a: | Cancer Sci |
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Autors principals: | , , , , , , |
Format: | Artigo |
Idioma: | Inglês |
Publicat: |
BlackWell Publishing Ltd
2015
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Matèries: | |
Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4376437/ https://ncbi.nlm.nih.gov/pubmed/25580850 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cas.12605 |
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