A targeted analysis identifies a high frequency of BRCA1 and BRCA2 mutation carriers in women with ovarian cancer from a founder population

BACKGROUND: The frequency of BRCA1 and BRCA2 mutations in ovarian cancer patients varies depending on histological subtype and population investigated. The six most commonly recurring BRCA1 and BRCA2 mutations previously identified in a founder French Canadian population were investigated in 439 his...

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Detalhes bibliográficos
Publicado no:J Ovarian Res
Main Authors: Belanger, Moria H, Dolman, Lena, Arcand, Suzanna L, Shen, Zhen, Chong, George, Mes-Masson, Anne-Marie, Provencher, Diane, Tonin, Patricia N
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4376165/
https://ncbi.nlm.nih.gov/pubmed/25884701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13048-015-0124-8
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