MicroRNA-33a regulates cholesterol synthesis and cholesterol efflux-related genes in osteoarthritic chondrocytes

INTRODUCTION: Several studies have shown that osteoarthritis (OA) is strongly associated with metabolism-related disorders, highlighting OA as the fifth component of the metabolic syndrome (MetS). On the basis of our previous findings on dysregulation of cholesterol homeostasis in OA, we were prompt...

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Vydáno v:Arthritis Res Ther
Hlavní autoři: Kostopoulou, Fotini, Malizos, Konstantinos N, Papathanasiou, Ioanna, Tsezou, Aspasia
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375845/
https://ncbi.nlm.nih.gov/pubmed/25880168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0556-y
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