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MicroRNA-33a regulates cholesterol synthesis and cholesterol efflux-related genes in osteoarthritic chondrocytes

INTRODUCTION: Several studies have shown that osteoarthritis (OA) is strongly associated with metabolism-related disorders, highlighting OA as the fifth component of the metabolic syndrome (MetS). On the basis of our previous findings on dysregulation of cholesterol homeostasis in OA, we were prompt...

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Bibliographische Detailangaben
Veröffentlicht in:Arthritis Res Ther
Hauptverfasser: Kostopoulou, Fotini, Malizos, Konstantinos N, Papathanasiou, Ioanna, Tsezou, Aspasia
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375845/
https://ncbi.nlm.nih.gov/pubmed/25880168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0556-y
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