A carregar...

DNA methylation regulates sclerostin (SOST) expression in osteoarthritic chondrocytes by bone morphogenetic protein 2 (BMP-2) induced changes in Smads binding affinity to the CpG region of SOST promoter

INTRODUCTION: Sclerostin (SOST), a soluble antagonist of Wnt signaling, is expressed in chondrocytes and contributes to chondrocytes’ hypertrophic differentiation; however its role in osteoarthritis (OA) pathogenesis is not well known. Based on our previous findings on the interaction between Wnt/β-...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Arthritis Res Ther
Main Authors: Papathanasiou, Ioanna, Kostopoulou, Fotini, Malizos, Konstantinos N., Tsezou, Aspasia
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491261/
https://ncbi.nlm.nih.gov/pubmed/26071314
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13075-015-0674-6
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!