Myosin S2 Origins Track Evolution of Strong Binding on Actin by Azimuthal Rolling of Motor Domain

Myosin crystal structures have given rise to the swinging lever arm hypothesis, which predicts a large axial tilt of the lever arm domain during the actin-attached working stroke. Previous work imaging the working stroke in actively contracting, fast-frozen Lethocerus muscle confirmed the axial tilt...

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Vydáno v:Biophys J
Hlavní autoři: Arakelian, Claudia, Warrington, Anthony, Winkler, Hanspeter, Perz-Edwards, R.J., Reedy, Michael K., Taylor, Kenneth A.
Médium: Artigo
Jazyk:Inglês
Vydáno: The Biophysical Society 2015
Témata:
Molecular Machines, Motors, and Nanoscale Biophysics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375447/
https://ncbi.nlm.nih.gov/pubmed/25809262
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2014.12.059
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