Reverse actin sliding triggers strong myosin binding that moves tropomyosin

Actin/myosin interactions in vertebrate striated muscles are believed to be regulated by the “steric blocking” mechanism whereby the binding of calcium to the troponin complex allows tropomyosin (TM) to change position on actin, acting as a molecular switch that blocks or allows myosin heads to inte...

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Hauptverfasser: Bekyarova, T. I., Reedy, M. C., Baumann, B. A. J., Tregear, R. T., Ward, A., Krzic, U., Prince, K. M., Perz-Edwards, R. J., Reconditi, M., Gore, D., Irving, T. C., Reedy, M. K.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2008
Schlagworte:
Biological Sciences
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2492518/
https://ncbi.nlm.nih.gov/pubmed/18658238
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0709877105
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