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cGMP interacts with tropomyosin and downregulates actin-tropomyosin-myosin complex interaction
BACKGROUND: The nitric oxide-soluble guanylate cyclase-cyclic guanosine monophosphate (NO-sGC-cGMP) signaling pathway, plays a critical role in the pathogenesis of pulmonary arterial hypertension (PAH); however, its exact molecular mechanism remains undefined. METHODS: Biotin-cGMP pull-down assay wa...
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| Опубликовано в: : | Respir Res |
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| Главные авторы: | , , , , , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
BioMed Central
2018
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6186101/ https://ncbi.nlm.nih.gov/pubmed/30314482 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-018-0903-z |
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