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The role of tropomyosin domains in cooperative activation of the actin-myosin interaction

To establish α–tropomyosin (Tm)’s structure-function relationships in cooperative regulation of muscle contraction, thin filaments were reconstituted with a variety of Tm mutants (Δ2Tm, Δ3Tm, Δ6Tm, P2sTm, P3sTm, P2P3sTm, P1P5Tm, wtTm), and force and sliding velocity of the thin filament were studied...

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Detalhes bibliográficos
Main Authors: Oguchi, Yusuke, Ishizuka, Junji, Hitchcock-DeGregori, Sarah E., Ishiwata, Shin’ichi, Kawai, Masataka
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3230701/
https://ncbi.nlm.nih.gov/pubmed/22041451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2011.10.026
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