Early Parkinson's disease symptoms in α-synuclein transgenic monkeys

Parkinson's disease (PD) is an age-dependent neurodegenerative disease that can be caused by genetic mutations in α-synuclein (α-syn) or duplication of wild-type α-syn; PD is characterized by the deposition of α-syn aggregates, indicating a gain of toxicity from accumulation of α-syn. Although...

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Publicado en:Hum Mol Genet
Main Authors: Niu, Yuyu, Guo, Xiangyu, Chen, Yongchang, Wang, Chuan-En, Gao, Jinquan, Yang, Weili, Kang, Yu, Si, Wei, Wang, Hong, Yang, Shang-Hsun, Li, Shihua, Ji, Weizhi, Li, Xiao-Jiang
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2015
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Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375423/
https://ncbi.nlm.nih.gov/pubmed/25552648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddu748
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