Replicability and Robustness of GWAS for Behavioral Traits

A recent genome-wide association study (GWAS) of educational attainment identified three single-nucleotide polymorphisms (SNPs) that, despite their small effect sizes (each R(2) ≈ 0.02%), reached genome-wide significance (p < 5×10(−8)) in a large discovery sample and replicated in an independent...

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Publicado en:Psychol Sci
Autores principales: Rietveld, Cornelius A., Conley, Dalton, Eriksson, Nicholas, Esko, Tõnu, Medland, Sarah E., Vinkhuyzen, Anna A.E., Yang, Jian, Boardman, Jason D., Chabris, Christopher F., Dawes, Christopher T., Domingue, Benjamin W., Hinds, David A., Johannesson, Magnus, Kiefer, Amy K., Laibson, David, Magnusson, Patrik K. E., Mountain, Joanna L., Oskarsson, Sven, Rostapshova, Olga, Teumer, Alexander, Tung, Joyce Y., Visscher, Peter M., Benjamin, Daniel J., Cesarini, David, Koellinger, Philipp D.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375246/
https://ncbi.nlm.nih.gov/pubmed/25287667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0956797614545132
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