Replicability and Robustness of GWAS for Behavioral Traits

A recent genome-wide association study (GWAS) of educational attainment identified three single-nucleotide polymorphisms (SNPs) that, despite their small effect sizes (each R(2) ≈ 0.02%), reached genome-wide significance (p < 5×10(−8)) in a large discovery sample and replicated in an independent...

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Vydáno v:Psychol Sci
Hlavní autoři: Rietveld, Cornelius A., Conley, Dalton, Eriksson, Nicholas, Esko, Tõnu, Medland, Sarah E., Vinkhuyzen, Anna A.E., Yang, Jian, Boardman, Jason D., Chabris, Christopher F., Dawes, Christopher T., Domingue, Benjamin W., Hinds, David A., Johannesson, Magnus, Kiefer, Amy K., Laibson, David, Magnusson, Patrik K. E., Mountain, Joanna L., Oskarsson, Sven, Rostapshova, Olga, Teumer, Alexander, Tung, Joyce Y., Visscher, Peter M., Benjamin, Daniel J., Cesarini, David, Koellinger, Philipp D.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375246/
https://ncbi.nlm.nih.gov/pubmed/25287667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0956797614545132
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