Replicability and Robustness of GWAS for Behavioral Traits

A recent genome-wide association study (GWAS) of educational attainment identified three single-nucleotide polymorphisms (SNPs) that, despite their small effect sizes (each R(2) ≈ 0.02%), reached genome-wide significance (p < 5×10(−8)) in a large discovery sample and replicated in an independent...

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Veröffentlicht in:Psychol Sci
Hauptverfasser: Rietveld, Cornelius A., Conley, Dalton, Eriksson, Nicholas, Esko, Tõnu, Medland, Sarah E., Vinkhuyzen, Anna A.E., Yang, Jian, Boardman, Jason D., Chabris, Christopher F., Dawes, Christopher T., Domingue, Benjamin W., Hinds, David A., Johannesson, Magnus, Kiefer, Amy K., Laibson, David, Magnusson, Patrik K. E., Mountain, Joanna L., Oskarsson, Sven, Rostapshova, Olga, Teumer, Alexander, Tung, Joyce Y., Visscher, Peter M., Benjamin, Daniel J., Cesarini, David, Koellinger, Philipp D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375246/
https://ncbi.nlm.nih.gov/pubmed/25287667
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/0956797614545132
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