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Severe Neonatal Holocarboxylase Synthetase Deficiency in West African Siblings

In multiple carboxylase deficiency (MCD), the biotin-dependent carboxylases have decreased activity due to either biotinidase deficiency or holocarboxylase synthetase (HS) deficiency. We report the case of two siblings from Ghana, the first of which presented shortly after birth with profound lactic...

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Detalhes bibliográficos
Publicado no:JIMD Rep
Main Authors: De Castro, Mauricio, Zand, Dina J., Lichter-Konecki, Uta, Kirmse, Brian
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375121/
https://ncbi.nlm.nih.gov/pubmed/25690727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/8904_2014_367
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