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Severe Neonatal Holocarboxylase Synthetase Deficiency in West African Siblings

In multiple carboxylase deficiency (MCD), the biotin-dependent carboxylases have decreased activity due to either biotinidase deficiency or holocarboxylase synthetase (HS) deficiency. We report the case of two siblings from Ghana, the first of which presented shortly after birth with profound lactic...

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Publicat a:JIMD Rep
Autors principals: De Castro, Mauricio, Zand, Dina J., Lichter-Konecki, Uta, Kirmse, Brian
Format: Artigo
Idioma:Inglês
Publicat: Springer Berlin Heidelberg 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4375121/
https://ncbi.nlm.nih.gov/pubmed/25690727
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/8904_2014_367
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