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Participation of target Fas protein in apoptosis pathway induced by CD4+ Th1 and CD8+ cytotoxic T cells.

The results presented here provide evidence that the presence of Fas protein in target cells is essential to permit cytotoxicity (resulting in apoptosis) mediated by cloned CD4+ Th1 cells. Using mitogen-activated B cells as targets, antigen-dependent lysis by CD4+ Th1 effectors was observed with MRL...

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Ju, S T, Cui, H, Panka, D J, Ettinger, R, Marshak-Rothstein, A
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 1994
Matèries:
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43749/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7514297/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.10.4185
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