CD95/Fas ligand mRNA is toxic to cells

CD95/Fas ligand binds to the death receptor CD95 to induce apoptosis in sensitive cells. We previously reported that CD95L mRNA is enriched in sequences that, when converted to si/shRNAs, kill all cancer cells by targeting critical survival genes (Putzbach et al., 2017). We now report expression of...

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主要な著者:	Will Putzbach, Ashley Haluck-Kangas, Quan Q Gao, Aishe A Sarshad, Elizabeth T Bartom, Austin Stults, Abdul S Qadir, Markus Hafner, Marcus E Peter
フォーマット:	Artigo
言語:	Inglês
出版事項:	eLife Sciences Publications Ltd 2018-10-01
シリーズ:	eLife
主題:	Fas DISE RNAi RISC
オンライン･アクセス:	https://elifesciences.org/articles/38621
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