CD95/Fas ligand mRNA is toxic to cells
CD95/Fas ligand binds to the death receptor CD95 to induce apoptosis in sensitive cells. We previously reported that CD95L mRNA is enriched in sequences that, when converted to si/shRNAs, kill all cancer cells by targeting critical survival genes (Putzbach et al., 2017). We now report expression of...
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| Auteurs principaux: | , , , , , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
eLife Sciences Publications Ltd
2018-10-01
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| Collection: | eLife |
| Sujets: | |
| Accès en ligne: | https://elifesciences.org/articles/38621 |
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