Participation of target Fas protein in apoptosis pathway induced by CD4+ Th1 and CD8+ cytotoxic T cells.

The results presented here provide evidence that the presence of Fas protein in target cells is essential to permit cytotoxicity (resulting in apoptosis) mediated by cloned CD4+ Th1 cells. Using mitogen-activated B cells as targets, antigen-dependent lysis by CD4+ Th1 effectors was observed with MRL...

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Pubblicato in:	Proc Natl Acad Sci U S A
Autori principali:	Ju, S T, Cui, H, Panka, D J, Ettinger, R, Marshak-Rothstein, A
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	National Academy of Sciences 1994
Soggetti:	Research Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC43749/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7514297/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.10.4185
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