Host APOBEC3G Protein Inhibits HCV Replication through Direct Binding at NS3

Human APOBEC3G (hA3G) is a cytidine deaminase that restricts replication of certain viruses. We have previously reported that hA3G was a host restriction factor against hepatitis C virus (HCV) replication, and hA3G stabilizers showed a significant inhibitory activity against HCV. However, the molecu...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Zhu, Yan-Ping, Peng, Zong-Gen, Wu, Zhou-Yi, Li, Jian-Rui, Huang, Meng-Hao, Si, Shu-Yi, Jiang, Jian-Dong
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374698/
https://ncbi.nlm.nih.gov/pubmed/25811715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121608
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