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APOBEC3G and APOBEC3F Require an Endogenous Cofactor to Block HIV-1 Replication
APOBEC3G (A3G)/APOBEC3F (A3F) are two members of APOBEC3 cytidine deaminase subfamily. Although they potently inhibit the replication of vif-deficient HIV-1, this mechanism is still poorly understood. Initially, A3G/A3F were thought to catalyze C-to-U transitions on the minus-strand viral cDNAs duri...
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| Auteurs principaux: | , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Public Library of Science
2008
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2435275/ https://ncbi.nlm.nih.gov/pubmed/18604271 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1000095 |
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