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Maternal Nicotine Exposure Leads to Impaired Disulfide Bond Formation and Augmented Endoplasmic Reticulum Stress in the Rat Placenta

Maternal nicotine exposure has been associated with many adverse fetal and placental outcomes. Although underlying mechanisms remain elusive, recent studies have identified that augmented endoplasmic reticulum (ER) stress is linked to placental insufficiency. Moreover, ER function depends on proper...

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Publicado en:PLoS One
Main Authors: Wong, Michael K., Nicholson, Catherine J., Holloway, Alison C., Hardy, Daniel B.
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374683/
https://ncbi.nlm.nih.gov/pubmed/25811377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122295
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