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Maternal Nicotine Exposure Leads to Impaired Disulfide Bond Formation and Augmented Endoplasmic Reticulum Stress in the Rat Placenta

Maternal nicotine exposure has been associated with many adverse fetal and placental outcomes. Although underlying mechanisms remain elusive, recent studies have identified that augmented endoplasmic reticulum (ER) stress is linked to placental insufficiency. Moreover, ER function depends on proper...

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Bibliographic Details
Published in:PLoS One
Main Authors: Wong, Michael K., Nicholson, Catherine J., Holloway, Alison C., Hardy, Daniel B.
Format: Artigo
Language:Inglês
Published: Public Library of Science 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374683/
https://ncbi.nlm.nih.gov/pubmed/25811377
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122295
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