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Two Pairs of Conserved Cysteines Are Required for the Oxidative Activity of Ero1p in Protein Disulfide Bond Formation in the Endoplasmic Reticulum

In the major pathway for protein disulfide-bond formation in the endoplasmic reticulum (ER), oxidizing equivalents flow from the conserved ER-membrane protein Ero1p to secretory proteins via protein disulfide isomerase (PDI). Herein, a mutational analysis of the yeast ERO1 gene identifies two pairs...

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Hlavní autoři: Frand, Alison R., Kaiser, Chris A.
Médium: Artigo
Jazyk:Inglês
Vydáno: The American Society for Cell Biology 2000
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC14959/
https://ncbi.nlm.nih.gov/pubmed/10982384
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