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Hypoxia-Inducible Factors Regulate Human and Rat Cystathionine β-Synthase Gene Expression

Increased catalytic activity of cystathionine β-synthase (CBS) was recently shown to mediate vasodilation of the cerebral microcirculation, which is initiated within minutes after the onset of acute hypoxia. To test whether chronic hypoxia was a stimulus for increased CBS expression, U87-MG human gl...

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Publicat a:Biochem J
Autors principals: Takano, Naoharu, Peng, Ying-Jie, Kumar, Ganesh K., Luo, Weibo, Hu, Hongxia, Shimoda, Larissa A., Suematsu, Makoto, Prabhakar, Nanduri R., Semenza, Gregg L.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374488/
https://ncbi.nlm.nih.gov/pubmed/24328859
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1042/BJ20131350
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