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Decreased Expression of Cystathionine β-Synthase Promotes Glioma Tumorigenesis

Cystathionine β-synthase (CBS) catalyzes metabolic reactions that convert homocysteine to cystathionine. To assess the role of CBS in human glioma, cells were stably transfected with lentiviral vectors encoding short hairpin RNA (shRNA) targeting CBS or a non-targeting control shRNA and subclones we...

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Detalhes bibliográficos
Publicado no:Mol Cancer Res
Main Authors: Takano, Naoharu, Sarfraz, Yasmeen, Gilkes, Daniele M., Chaturvedi, Pallavi, Xiang, Lisha, Suematsu, Makoto, Zagzag, David, Semenza, Gregg L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4274393/
https://ncbi.nlm.nih.gov/pubmed/24994751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1541-7786.MCR-14-0184
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