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SULF2 overexpression positively regulates tumorigenicity of human prostate cancer cells

BACKGROUND: SULF2 is a 6-O-endosulfatase which removes 6-O sulfate residues from N-glucosamine present on heparan sulfate (HS). The sulfation pattern of HS influences signaling events mediated by heparan sulfate proteoglycans (HSPGs) located on cell surface, which are critical for the interactions w...

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發表在:J Exp Clin Cancer Res
Main Authors: Vicente, Carolina M, Lima, Marcelo A, Nader, Helena B, Toma, Leny
格式: Artigo
語言:Inglês
出版: BioMed Central 2015
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374423/
https://ncbi.nlm.nih.gov/pubmed/25887999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-015-0141-x
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