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SULF2 overexpression positively regulates tumorigenicity of human prostate cancer cells

BACKGROUND: SULF2 is a 6-O-endosulfatase which removes 6-O sulfate residues from N-glucosamine present on heparan sulfate (HS). The sulfation pattern of HS influences signaling events mediated by heparan sulfate proteoglycans (HSPGs) located on cell surface, which are critical for the interactions w...

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Detalhes bibliográficos
Publicado no:J Exp Clin Cancer Res
Main Authors: Vicente, Carolina M, Lima, Marcelo A, Nader, Helena B, Toma, Leny
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374423/
https://ncbi.nlm.nih.gov/pubmed/25887999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-015-0141-x
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