AFAP-110 is overexpressed in prostate cancer and contributes to tumorigenic growth by regulating focal contacts

The actin filament–associated protein AFAP-110 is an actin cross-linking protein first identified as a substrate of the viral oncogene v-Src. AFAP-110 regulates actin cytoskeleton integrity but also functions as an adaptor protein that affects crosstalk between Src and PKC. Here we investigated the...

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Main Authors: Zhang, Jing, Park, Serk In, Artime, Marlene C., Summy, Justin M., Shah, Ami N., Bomser, Joshua A., Dorfleutner, Andrea, Flynn, Daniel C., Gallick, Gary E.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2007
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC1978423/
https://ncbi.nlm.nih.gov/pubmed/17885682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI30710
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