Successful control of heavily pretreated metastatic gastric cancer with the mTOR inhibitor everolimus (RAD001) in a patient with PIK3CA mutation and pS6 overexpression

BACKGROUND: Everolimus (RAD001) is an orally administered mTOR inhibitor that is well known for its antitumor efficacy and that has been approved for the treatment of several solid tumors, including renal cell carcinoma. In gastric cancer (GC), despite previous preclinical and phase I/II studies sug...

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Bibliografiske detaljer
Udgivet i:BMC Cancer
Main Authors: Park, Ji Hyun, Ryu, Min-Hee, Park, Young Soo, Park, Sook Ryun, Na, Young-Soon, Rhoo, Baek-Yeol, Kang, Yoon-Koo
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2015
Fag:
Case Report
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4374284/
https://ncbi.nlm.nih.gov/pubmed/25886409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1139-7
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