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Angiotensin II-Induced Arterial Thickening, Fibrosis and Stiffening Involves Elevated Arginase Function
BACKGROUND: Arterial stiffness (AS) is an independent risk factor for cardiovascular morbidity/mortality. Smooth muscle cell (SMC) proliferation and increased collagen synthesis are key features in development of AS. Arginase (ARG), an enzyme implicated in many cardiovascular diseases, can compete w...
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Vydáno v: | PLoS One |
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Hlavní autoři: | , , , , , , |
Médium: | Artigo |
Jazyk: | Inglês |
Vydáno: |
Public Library of Science
2015
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Témata: | |
On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4373900/ https://ncbi.nlm.nih.gov/pubmed/25807386 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0121727 |
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