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ORMDL/serine palmitoyltransferase stoichiometry determines effects of ORMDL3 expression on sphingolipid biosynthesis

The ORM1 (Saccharomyces cerevisiae)-like proteins (ORMDLs) and their yeast orthologs, the Orms, are negative homeostatic regulators of the initiating enzyme in sphingolipid biosynthesis, serine palmitoyltransferase (SPT). Genome-wide association studies have established a strong correlation between...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:J Lipid Res
मुख्य लेखकों: Siow, Deanna, Sunkara, Manjula, Dunn, Teresa M., Morris, Andrew J., Wattenberg, Binks
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: The American Society for Biochemistry and Molecular Biology 2015
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC4373746/
https://ncbi.nlm.nih.gov/pubmed/25691431
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.M057539
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