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Does autophagy take a front seat in lifespan extension?

This review focuses on the interrelationship between ageing and autophagy. There is a striking similarity between the signalling aspects of these two processes. Both ageing and autophagy involve several of the signalling components such as insulin/IGF-1, AMPK, Ras-cAMP-PKA, Sch9 and mTOR. Ageing and...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Main Authors: Petrovski, Goran, Das, Dipak K
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4373474/
https://ncbi.nlm.nih.gov/pubmed/21114762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2010.01196.x
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