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Mitochondrial Permeability Uncouples Elevated Autophagy and Lifespan Extension
Autophagy is required in diverse paradigms of lifespan extension, leading to the prevailing notion that autophagy is beneficial for longevity. However, why autophagy is harmful in certain contexts, remains unexplained. Here we show that mitochondrial permeability defines the impact of autophagy on a...
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| Publicado no: | Cell |
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| Main Authors: | , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6610881/ https://ncbi.nlm.nih.gov/pubmed/30929899 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2019.02.013 |
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