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Differential requirements for Gli2 and Gli3 in the regional specification of the mouse hypothalamus

Secreted protein Sonic hedgehog (Shh) ventralizes the neural tube by modulating the crucial balance between activating and repressing functions (GliA, GliR) of transcription factors Gli2 and Gli3. This balance—the Shh-Gli code—is species- and context-dependent and has been elucidated for the mouse s...

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Detalhes bibliográficos
Publicado no:Front Neuroanat
Main Authors: Haddad-Tóvolli, Roberta, Paul, Fabian A., Zhang, Yuanfeng, Zhou, Xunlei, Theil, Thomas, Puelles, Luis, Blaess, Sandra, Alvarez-Bolado, Gonzalo
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4373379/
https://ncbi.nlm.nih.gov/pubmed/25859185
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fnana.2015.00034
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